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Anti-COTL1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K112332P - SAlexa Fluor 488
Summary:
【Product name】:Anti-COTL1 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:23406 【Swiss Prot】:Q14019
【Observed】:16kDa
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human COTL1
【Public Immunogen Range】:1-143aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
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