Anti-TNNT2 Polyclonal Antibody
Cat: K112333P
Summary:
| 【Product name】：Anti-TNNT2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：7139 | 【Swiss Prot】：P45379 |
| 【Observed】：35/46kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human TNNT2 | |
| 【Public Immunogen Range】：1-286aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Verified picture:
Western blot analysis with TNNT2 antibody diluted at 1:2000;Lane: Rat heart
Immunohistochemistry of paraffin-embedded rat heart with TNNT2 antibody diluted at 1:50.