Summary:
activin A receptor, type IC
Cat：P06540
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 144-494aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ACVR1C |
| 【Full Name】： activin A receptor，type IC |
| 【Uniprot】： Q8NER5 |
| 【Gene ID】： 130399 |
| 【Species Reactivity】： Human Mouse Rat |
| 【Mol Mass】： 40kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate then bind and activate SMAD transcriptional regulators SMAD2 and SMAD3. Receptor for activin AB activin B and NODAL. Plays a role in cell differentiation growth arrest and apoptosis.
Verified picture
