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histone cluster 1, H2bo

Cat:P07773

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-127aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: HIST1H2BO
【Full Name】: histone cluster 1,H2bo
【Uniprot】: P23527
【Gene ID】: 8348
【Mol Mass】: 14kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

H2BC17 H2BFH,H2BFN,Core component of nucleosome.Nucleosomes wrap and compact DNA into chromatin,limiting DNA accessibility to the cellular machineries which require DNA as a template.Histones thereby play a central role in transcription regulation,DNA repair,DNA replication and chromosomal stability.DNA accessibility is regulated via a complex set of post-translational modifications of histones,also called histone code,and nucleosome remodeling.

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