Summary:
Recombinant human LRRC1 protein
Cat：P08003
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 170-520aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： LRRC1 |
| 【Full Name】： leucine rich repeat containing 1 |
| 【Uniprot】： Q9BTT6 |
| 【Gene ID】： 55227 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 39kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic /∫ horseshoe fold，allowing it to accommodate several leucine residues within a tightly packed core.All LRR repeats contain a variable segment and a highly conserved segment，the latter of which accounts for 11 or 12 residues of the entire LRR motif.The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions.LRRs are present in a variety of proteins with diverse structure and function，including innate immunity and nervous system development.LRRC1 (leucine-rich repeat-containing protein 1)，also known as LANO adapter protein or LAP and no PDZ protein，is a 524 amino acid protein that contains 17 LRR repeats.Localized to the cytoplasm and the membrane，LRRC1 is expressed strongly in placenta and testis，with lower levels found in heart，kidney，thyroid，lung，prostate，colon and trachea.LRRC1 interacts with PSD-95 and SAP 97，and may
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