Summary:
Recombinant human MARCHF2 protein
Cat：P08344
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-142AA |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： MARCHF2 |
| 【Full Name】： membrane-associated ring finger (C3HC4) 2 |
| 【Uniprot】： Q9P0N8 |
| 【Gene ID】： 51257 |
| 【Species Reactivity】： Human |
| 【Mol Mass】： 15.3kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86，and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies.E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates (PubMed:14722266，PubMed:16428329).
Verified picture
