PFKM Antibody Blocking Peptide

Three phosphofructokinase isozymes exist in humans: muscle， liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase， which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1，6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII， also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq， Nov 2009]