Summary:
BMP2 Antibody Blocking Peptide
Cat：K101544P-Ag
| 【Derived From】： Synthetic |
| 【Uniprot】： P21274 |
| 【Gene ID】： 12156 |
| 【Application】： Blocking Peptide of K101544P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119， which upregulates the expression of ATF4.
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