NALP4 Antibody Blocking Peptide

May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1， and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B， suggesting that it operates at a point of convergence in these two cytokine signaling pathways.