下载

SIGIRR Antibody Blocking Peptide

Cat:K113503P-Ag

Summary:

【Derived From】: Synthetic
【Amino Acid】: 295-345/410aa
【Uniprot】: Q6IA17
【Gene ID】: 59307
【Application】: Blocking Peptide of K113503P Antibody
【Purification】: HPLC
【Bioactive】: Not tested

Store:

【Storage】: Store at -20℃,2 years.Avoid freeze/thaw cycles.
【Formulation】: Lyophilized powder

Background:

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Verified picture