Summary:
STIMATE Antibody Blocking Peptide
Cat：K113510P-Ag
| 【Derived From】： Synthetic |
| 【Amino Acid】： 100-150/294aa |
| 【Uniprot】： Q86TL2 |
| 【Gene ID】： 375346 |
| 【Application】： Blocking Peptide of K113510P Antibody |
| 【Purification】： HPLC |
| 【Bioactive】： Not tested |
Store:
| 【Storage】： Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| 【Formulation】： Lyophilized powder |
Background:
Acts as a regulator of store-operated Ca2+ entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM)， called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679， PubMed:26644574).SOCE is a Ca2+ influx following depletion of intracellular Ca2+ stores (PubMed:26322679).Acts by interacting with STIM1， promoting STIM1 conformational switch (PubMed:26322679).Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574).Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574).
Verified picture
