Summary:
Recombinant human DCN protein
Cat：P02548
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-359aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： DCN |
| 【Full Name】： decorin |
| 【Uniprot】： P07585 |
| 【Gene ID】： 1634 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Dog Horse Rabbit Pig Sheep Chicken) |
| 【Mol Mass】： 40kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the small leucine-rich proteoglycan family of proteins.Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein.This protein plays a role in collagen fibril assembly.Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis.This gene and the related gene biglycan are thought to be the result of a gene duplication.Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients
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