Summary:
Recombinant human ACTG1 protein
Cat：P02554
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-375aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ACTG1 |
| 【Full Name】： actin，gamma 1 |
| 【Uniprot】： P63261 |
| 【Gene ID】： 71 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Pig Chicken Horse Dog Gorilla) |
| 【Mol Mass】： 42kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton.In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified.The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus.The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility.Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells.Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss.Alternative splicing results in multiple transcript variants.
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