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Recombinant human MTRF1L protein

Cat:P02574

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-380aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: MTRF1L
【Full Name】: mitochondrial translational release factor 1-like
【Uniprot】: Q9UGC7
【Gene ID】: 54516
【Species Reactivity】: Human Mouse Rat (Bovine)
【Mol Mass】: 44kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA.This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG.This protein shares sequence similarity to bacterial release factors.Pseudogenes of this gene are found on chromosomes 4, 8, and 11.Alternative splicing results in multiple transcript variants.

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