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Recombinant human ACTR1A protein

Cat:P02580

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-377aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: ACTR1A
【Full Name】: ARP1 actin-related protein 1 homolog A,centractin alpha (yeast)
【Uniprot】: P61163
【Gene ID】: 10121
【Species Reactivity】: Human Mouse Rat (Dog Monkey)
【Mol Mass】: 40kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD.Dynactin binds to both microtubules and cytoplasmic dynein.It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis.This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex.It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

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