Summary:
Recombinant human RAB7A protein
Cat：P02591
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-207aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： RAB7A |
| 【Full Name】： RAB7A，member RAS oncogene family |
| 【Uniprot】： P51149 |
| 【Gene ID】： 7879 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Dog Rabbit Gorilla A.thaliana) |
| 【Mol Mass】： 23kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport.Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways.This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes.This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori.Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
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