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Recombinant human CSNK2B protein

Cat:P02605

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-215aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: CSNK2B
【Full Name】: casein kinase 2,beta polypeptide
【Uniprot】: P67870
【Gene ID】: 1460
【Species Reactivity】: Human Mouse Rat (Bovine Zebrafish Pig Chicken Rabbit)
【Mol Mass】: 25kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication.The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme.The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions.The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.Two transcript variants encoding different isoforms have been found for this gene.

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