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Recombinant human NONO protein

Cat:P02620

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-471aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: NONO
【Full Name】: non-POU domain containing,octamer-binding
【Uniprot】: Q15233
【Gene ID】: 4841
【Species Reactivity】: Human Mouse Rat (Gorilla)
【Mol Mass】: 54kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing.A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma.Alternatively spliced transcript variants have been described.Pseudogenes exist on Chromosomes 2 and 16.

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