下载

Recombinant human SNF8 protein

Cat:P02635

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-258aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SNF8
【Full Name】: SNF8,ESCRT-II complex subunit,homolog (S. cerevisiae)
【Uniprot】: Q96H20
【Gene ID】: 11267
【Species Reactivity】: Human Mouse Rat (Zebrafish)
【Mol Mass】: 29kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation.This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity.Several transcript variants encoding different isoforms have been found for this gene.

Verified picture