Summary:
Recombinant human GNB1L protein
Cat：P02639
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-327aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： GNB1L |
| 【Full Name】： guanine nucleotide binding protein (G protein)，beta polypeptide 1-like |
| 【Uniprot】： Q9BYB4 |
| 【Gene ID】： 54584 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 36kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family.WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes.Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.This protein contains 6 WD repeats and is highly expressed in the heart.The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome.Therefore, this gene may contribute to the etiology of those disorders.Transcripts from this gene share exons with some transcripts from the C22orf29 gene.
Verified picture
