Summary:
Recombinant human YWHAE protein
Cat：P02640
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-255aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： YWHAE |
| 【Full Name】： tyrosine 3-monooxygenase |
| 【Uniprot】： P62258 |
| 【Gene ID】： 7531 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Sheep Chicken) |
| 【Mol Mass】： 29kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins.This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog.It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity.It has also been implicated in the pathogenesis of small cell lung cancer.Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
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