Summary:
Recombinant human PRDX2 protein
Cat：P02641
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-198aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： PRDX2 |
| 【Full Name】： peroxiredoxin 2 |
| 【Uniprot】： P32119 |
| 【Gene ID】： 7001 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Pig Monkey Gorilla) |
| 【Mol Mass】： 22kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides.The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells.The crystal structure of this protein has been resolved to 2.7 angstroms.This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia.This protein may have a proliferative effect and play a role in cancer development or progression.Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
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