Summary:
Recombinant human BTG1 protein
Cat：P02647
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-171aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： BTG1 |
| 【Full Name】： B-cell translocation gene 1 |
| 【Uniprot】： P62324 |
| 【Gene ID】： 694 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Chicken) |
| 【Mol Mass】： 19kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation.Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1.The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation.This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
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