Summary:
Recombinant human RPS6KB1 protein
Cat：P02664
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-350aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： RPS6KB1 |
| 【Full Name】： ribosomal protein S6 kinase，70kDa，polypeptide 1 |
| 【Uniprot】： P23443 |
| 【Gene ID】： 6198 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Rabbit) |
| 【Mol Mass】： 39kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases.The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation.Activity of this gene has been associated with human cancer.Alternatively spliced transcript variants have been observed.The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations.There are two pseudogenes for this gene on chromosome 17.
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