Summary:
Recombinant human CP110 protein
Cat：P02669
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-337aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CP110 |
| 【Full Name】： CP110 |
| 【Uniprot】： O43303 |
| 【Gene ID】： 9738 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Necessary for centrosome duplication at different stages of procentriole formation.Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.Also involved in promoting ciliogenesis.May play a role in the assembly of the mother centriole subdistal appendages thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation.Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.
Verified picture
