Summary:
Recombinant human CEP19 protein
Cat：P02677
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-163aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CEP19 |
| 【Full Name】： Centrosomal protein of 19 kDa，Cep19 |
| 【Uniprot】： Q96LK0 |
| 【Gene ID】： 84984 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Zebrafish) |
| 【Mol Mass】： 19kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole.This gene resides in a region of human chromosome 3 that is linked to morbid obesity.A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance.Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF).This gene has a pseudogene on human chromosome 2.
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