Summary:
Recombinant human EDN1 protein
Cat：P02688
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-212aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： EDN1 |
| 【Full Name】： endothelin 1 |
| 【Uniprot】： P05305 |
| 【Gene ID】： 1906 |
| 【Species Reactivity】： Human Mouse Rat (Rabbit Bovine Pig Sheep Monkey) |
| 【Mol Mass】： 24kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family.This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension.Aberrant expression of this gene may promote tumorigenesis.Alternative splicing results in multiple transcript variants.
Verified picture
