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Recombinant human GSTT1 protein

Cat:P02692

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-240aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: GSTT1
【Full Name】: glutathione S-transferase theta 1
【Uniprot】: P30711
【Gene ID】: 2952
【Species Reactivity】: Human Mouse Rat (Bovine Chicken A.thaliana)
【Mol Mass】: 27kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds.Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta.The theta class includes GSTT1 and GSTT2.The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis.The GSTT1 gene is located approximately 50kb away from the GSTT2 gene.The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

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