Summary:
Recombinant human OSM protein
Cat：P02719
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 24-252aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： OSM |
| 【Full Name】： oncostatin M |
| 【Uniprot】： P13725 |
| 【Gene ID】： 5008 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Fruit fly A.thaliana) |
| 【Mol Mass】： 28kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines.This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells.This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene.Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).
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