Summary:
Recombinant human BAAT protein
Cat：P02728
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-418aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： BAAT |
| 【Full Name】： bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) |
| 【Uniprot】： Q14032 |
| 【Gene ID】： 570 |
| 【Species Reactivity】： Human Mouse Rat |
| 【Mol Mass】： 46kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates.The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption.Defects in this gene are a cause of familial hypercholanemia (FHCA).Two transcript variants encoding the same protein have been found for this gene.
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