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Recombinant human ACTA2 protein

Cat:P02732

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-377aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: ACTA2
【Full Name】: actin,alpha 2,smooth muscle,aorta
【Uniprot】: P62736
【Gene ID】: 59
【Species Reactivity】: Human Mouse Rat (Bovine Rabbit Chicken)
【Mol Mass】: 42kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity.Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility.This actin is an alpha actin that is found in skeletal muscle.Defects in this gene cause aortic aneurysm familial thoracic type 6.Multiple alternatively spliced variants, encoding the same protein, have been identified.

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