Summary:
Recombinant human DNAJA1 protein
Cat：P02746
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-397aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： DNAJA1 |
| 【Full Name】： DnaJ (Hsp40) homolog，subfamily A，member 1 |
| 【Uniprot】： P31689 |
| 【Gene ID】： 3301 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Gorilla Monkey) |
| 【Mol Mass】： 45kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones.Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation.Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain.The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity.In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus.Several pseudogenes of this gene are found on other chromosomes.
Verified picture
