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Recombinant human NASP protein

Cat:P02750

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 439-788aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: NASP
【Full Name】: nuclear autoantigenic sperm protein (histone-binding)
【Uniprot】: P49321
【Gene ID】: 4678
【Species Reactivity】: Human Mouse Rat (Bovine Rabbit)
【Mol Mass】: 39kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells.Multiple isoforms are encoded by transcript variants of this gene.The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle.The testicular form is expressed in embryonic tissues, tumor cells, and the testis.In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.

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