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Recombinant human CTBP2 protein

Cat:P02760

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-204aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: CTBP2
【Full Name】: C-terminal binding protein 2
【Uniprot】: P56545
【Gene ID】: 1488
【Species Reactivity】: Human Mouse Rat (Bovine)
【Mol Mass】: 23kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene produces alternative transcripts encoding two distinct proteins.One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons.Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases.A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely.Blast analysis shows that this gene is present on chromosome 10.Several transcript variants encoding two different isoforms have been found for this gene.

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