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Recombinant human CCNB2 protein

Cat:P02770

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-280aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: CCNB2
【Full Name】: cyclin B2
【Uniprot】: O95067
【Gene ID】: 9133
【Species Reactivity】: Human Mouse (Bovine Chicken Monkey)
【Mol Mass】: 32kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins.The B-type cyclins, B1 and B2 associate with p34cdc2 and essential for the control of the cell cycle at the G2/M (mitosis) transition.B1 and B2 differ in their subcellular localization.Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region.Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

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