Summary:
Recombinant human LPXN protein
Cat：P02897
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-386aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： LPXN |
| 【Full Name】： leupaxin |
| 【Uniprot】： O60711 |
| 【Gene ID】： 9404 |
| 【Species Reactivity】： Human Mouse (Rabbit) |
| 【Mol Mass】： 43kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family.Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus.It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family.As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity.Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Verified picture
