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Recombinant human CHAC2 protein

Cat:P02905

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-184aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: CHAC2
【Full Name】: Glutathione-specific gamma-glutamylcyclotransferase 2
【Uniprot】: Q8WUX2
【Gene ID】: 494143
【Species Reactivity】: Human Mouse Rat (Bovine Chicken Zebrafish)
【Mol Mass】: 21kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine.It is thought that this gene is upregulated in response to endoplasmic reticulum stress and that the glutathione depletion enhances apoptosis.

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