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Recombinant human FHL3 protein

Cat:P02908

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-280aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: FHL3
【Full Name】: four and a half LIM domains 3
【Uniprot】: Q13643
【Gene ID】: 2275
【Species Reactivity】: Human Mouse (Bovine)
【Mol Mass】: 31kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif.The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1.This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]

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