下载

Recombinant human RNF40 protein

Cat:P02921

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 652-1001aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: RNF40
【Full Name】: ring finger protein 40
【Uniprot】: O75150
【Gene ID】: 9810
【Species Reactivity】: Human Mouse Rat (Gorilla Monkey)
【Mol Mass】: 38kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions.This protein was reported to interact with the tumor suppressor protein RB1.Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Verified picture