Summary:
Recombinant human YTHDF2 protein
Cat：P02940
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 230-579aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： YTHDF2 |
| 【Full Name】： YTH domain family，member 2 |
| 【Uniprot】： Q9Y5A9 |
| 【Gene ID】： 51441 |
| 【Species Reactivity】： Human Mouse (2 Zebrafish Monkey) |
| 【Mol Mass】： 39kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain.The YTH domain is typical for the eukaryotes and is particularly abundant in plants.The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA.In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction.An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity.In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia.This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Verified picture
