Summary:
Recombinant human TGFBI protein
Cat：P02955
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 352-683aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： TGFBI |
| 【Full Name】： Transforming growth factor-beta-induced protein ig-h3 |
| 【Uniprot】： Q15582 |
| 【Gene ID】： 7045 |
| 【Species Reactivity】： Human Mouse (Bovine Rabbit Pig) |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens.The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins.This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage.The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.Mutations in this gene are associated with multiple types of corneal dystrophy.
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