Summary:
Recombinant human TXNL4A protein
Cat：P02979
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-142aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： TXNL4A |
| 【Full Name】： thioredoxin-like 4A |
| 【Uniprot】： P83876 |
| 【Gene ID】： 10907 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 17kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing.This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins.Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1).Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia.A pseudogene of this gene is found on chromosome 2.Alternative splicing results in multiple transcript variants.
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