Summary:
Recombinant human EIF4A2 protein
Cat：P03003
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-407aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： EIF4A2 |
| 【Full Name】： eukaryotic translation initiation factor 4A，isoform 2 |
| 【Uniprot】： Q14240 |
| 【Gene ID】： 1974 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Gorilla Chicken Monkey) |
| 【Mol Mass】： 46kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins.RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes.They drive G proteins into their inactive GDP-bound forms.Regulator of G protein signaling 4 belongs to this family.All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain.Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4.This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Alternatively spliced transcript variants have been found for this gene.
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