Summary:
Recombinant human ACTR8 protein
Cat：P03019
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 296-624aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ACTR8 |
| 【Full Name】： Actin-related protein 8 |
| 【Uniprot】： Q9H981 |
| 【Gene ID】： 93973 |
| 【Species Reactivity】： Human Mouse (Bovine Gorilla Zebrafish) |
| 【Mol Mass】： 37kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Plays an important role in the functional organization of mitotic chromosomes.Exhibits low basal ATPase activity, and unable to polymerize.Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage.Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.
Verified picture
