Summary:
Recombinant human GEMIN8 protein
Cat：P03040
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-242aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： GEMIN8 |
| 【Full Name】： Gem-associated protein 8 |
| 【Uniprot】： Q9NWZ8 |
| 【Gene ID】： 54960 |
| 【Species Reactivity】： Human Mouse (Bovine) |
| 【Mol Mass】： 29kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus.The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction.This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm.Three transcript variants encoding the same protein have been found for this gene.
Verified picture
