Summary:
Recombinant human MDFI protein
Cat：P03041
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-246aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： MDFI |
| 【Full Name】： MyoD family inhibitor |
| 【Uniprot】： Q99750 |
| 【Gene ID】： 4188 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 25kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This protein is a transcription factor that negatively regulates other myogenic family proteins.Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding.Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures
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