Summary:
Recombinant human CDRT4 protein
Cat：P03057
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-152aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CDRT4 |
| 【Full Name】： CMT1A duplicated region transcript 4 |
| 【Uniprot】： Q8N9R6 |
| 【Gene ID】： 284040 |
| 【Species Reactivity】： Human Mouse (Bovine) |
| 【Mol Mass】： 18kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene is a member of the interleukin 1 cytokine family.This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses.This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2.A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
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