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Recombinant human AP1S2 protein

Cat:P03084

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-157aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: AP1S2
【Full Name】: adaptor-related protein complex 1,sigma 2 subunit
【Uniprot】: P56377
【Gene ID】: 8905
【Species Reactivity】: Human Mouse (Bovine)
【Mol Mass】: 19kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors.This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit.The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family.Transcript variants encoding different isoforms have been found for this gene.

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