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Recombinant human KCNE4 protein

Cat:P03104

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 52-221aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: KCNE4
【Full Name】: potassium voltage-gated channel,Isk-related family,member 4
【Uniprot】: Q8WWG9
【Gene ID】: 23704
【Species Reactivity】: Human Mouse
【Mol Mass】: 24kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints.Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily.This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex.This gene is prominently expressed in the embryo and in adult uterus.

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