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Recombinant human HOXB13 protein

Cat:P03130

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-284aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: HOXB13
【Full Name】: Homeobox protein Hox-B13
【Uniprot】: Q92826
【Gene ID】: 10481
【Species Reactivity】: Human Mouse (Zebrafish)
【Mol Mass】: 31kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a transcription factor that belongs to the homeobox gene family.Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development.This gene has been implicated to play a role in fetal skin development and cutaneous regeneration.In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis.This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.

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